Sulfamethoxazole is primarily renally excreted via glomerular filtration and tubular secretion.
2.
But many drugs are cleared by tubular secretion.
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Glomerular filtration, active tubular secretion, and tubular reabsorption are the main processes involved.
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It is eliminated mainly by tubular secretion.
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Research indicates doripenem is filtered by the glomerular capillary bed in Bowman s capsule and the tubular secretions in the nephron.
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Creatinine is removed from the blood chiefly by the kidneys, primarily by glomerular filtration, but also by proximal tubular secretion.
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Tenofovir is mainly excreted via the kidneys, both by glomerular filtration and by tubular secretion using the transport proteins OAT1, OAT3 and ABCC4.
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Metformin is not tubular secretion and excreted unchanged in the urine; metformin is undetectable in blood plasma within 24 hours of a single oral dose.
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Renal excretion occurs by both glomerular filtration and tubular secretion as evidenced by the high rate of renal clearance ( approximately 275 mL / min ).
10.
The mean renal clearance for trospium ( 29 L / hour ) is 4-fold higher than average glomerular filtration rate, indicating that active tubular secretion is a major route of elimination for trospium.
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